First discussing what qualifies as palliative care, Simon Noble, MBBS, Cardiff University, Cardiff, UK, explains cancer associated thrombosis (CAT) treatment in this context. Despite the limitations of data, it appears that anticoagulation during the end of life confers a bleeding risk without additional benefit of symptom control. This interview took place at the International Society of Oncology Pharmacy Practitioners (ISOPP) Symposium 2019, hosted by the British Oncology Pharmacy Association (BOPA), held in London, UK.